Viral RNA Extraction

Reagent Kits: RNAdvance Viral or RNAdvance Viral XP

Extract high-quality RNA from Saliva or Swab Transport Media samples using SPRI paramagnetic bead-based technology. Our viral RNA extraction kits are available for your unique input sample types and collection devices. RNAdvance Viral XP offers higher throughput capabilities and the RNAdvance Viral kit is optimal for extracting from a variety of challenging sample inputs.

  • Produces high-integrity viral RNA for use with PCR-based applications for infectious disease and pathogen research
  • Performance Limit of Detection (LoD) demonstrated at 1 copy/uL for viral RNA
  • Automation-ready, viral extraction quickly adapted to liquid handling platforms

Technical Documents:

For research use, not intended for diagnostic purposes.

 

Resources + Tools
Performance Automated Workflow Application Note Customer Interview Testimonial White Paper
RNAdvance Viral reagent kit isolates RNA from Saliva and Swab Transport Media
RNA Isolation from Viral Samples RNAdvance Viral XP Reagent Kit

Explore Viral Models

RNAdvance Viral Workflow Steps

RNA Isolation from Viral Samples Workflow with RNAdvance Viral XP

RNAdvance Viral Product Features

Overview
RNAdvance Viral XP isolates RNA from Universal Transport Media. RNAdvance Viral isolates RNA from Saliva and Swab Transport Media.

High-Quality RNA
The RNAdvance Viral XP and RNAdvance Viral isolation kits purify intact RNA suitable for downstream PCR-based applications. Limit of Detection (LoD) of 1 copy/µL for viral RNA.

Flexible and Scalable
Combining RNAdvance Viral chemistry with automation offers a high-throughput processing solution requiring minimal hands-on-time.

RNAdvance Viral Product Specifications

Application Uses Research Use, RNA Isolation, RNA Extraction, Nucleic Acid Sample Prep, PCR
Format Liquid
Starting Sample Material Saliva and Swab in Universal Transport Media
Automated Available Yes
Item Specifications Referenced C63510

Product Launch Video: RNAdvance Viral XP Reagent Kit

Content and Resources

High-throughput qPCR and RT-qPCR Workflows Enabled by Beckman Coulter Echo Acoustic Liquid Handling and NEB® Luna® Reagents Application Note: We show that NEB Luna qPCR reagents offer strong performance in high-throughput qPCR applications and are readily compatible with automated reaction setup, here using the Beckman Echo 525 acoustic liquid handler.
Characterization of the Beckman Coulter's RNAdvance Viral XP RNA Extraction Kit using AccuPlex™ SARS–CoV–2 Reference Material Kit White Paper: iRepertoire performed analytical performance assays and specimen assays to demonstrate that the RNAdvance Viral XP extraction kit has a limit of detection of RNA (LoD) of 1 copy of RNA, specifically tested with AccuPlex™ SARS–CoV–2 Reference Material Kit, per microliter of sample.
Inactivation of COVID-19 disease virus SARS-CoV-2 with Beckman Coulter viral RNA extraction lysis buffers White Paper: We conducted experiments to assess the virus inactivation status after treatment with lysis buffer (LBF) from RNAdvance Viral or RNAdvance Viral XP extraction kits.
Infectious Disease-based Pandemic Monitoring using Distributed Sewer Water Samples Poster: In this proof of principle study, we demonstrate RNAdvance Viral RNA extraction method that's compatible with different wastewater concentration methods.
Robust and High-Throughput SARS-CoV-2 Viral RNA Detection, Research, and Sequencing using RNAdvance Viral and the OT-2 Platform Application Note: We present analytical data showing the SARS-CoV-2 limit of detection (LoD) quantified by qRT-PCR and sequence alignment data that establishes proof of principle for automated sequencing sample and library preparation for possible genetic identification of mutated strains.

Technical Documents

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