Application Notes

The real-world benefits provided by our technologies are realized only through their application. 

Our growing repository of application notes runs the gamut of topics—from cutting-edge research on genomic and biopharmaceutical therapies to total organic carbon analysis for modern water systems.

Content and Resources

Aerobic cultivation of high-oxygen-demanding microorganisms in the BioLector XT microbioreactor
Anaerobic cultivation processes of probiotic bacteria in the BioLector XT microbioreactor
Analyzing Mussel/Mollusk Propagation using the Multisizer 4e Coulter Counter
Temperature dependence of hydrodynamic radius of an intrinsically disordered protein measured in the Optima AUC analytical ultracentrifuge. Analytical ultracentrifugation experiments over a wide range of temperatures were conducted to measure the hydrodynamic radius of an intrinsically disordered protein. Taking advantage of the highly stable temperature control offered through the latest shroud modification available in the new Optima AUC, replicate experiments demonstrated highly reproducible hydrodynamic parameters that suggest slight changes in the hydrodynamic radius of an intrinsically disordered protein, and impressive performance in both temperature control and data quality from the Optima AUC.
Multi-Wavelength Analytical Ultracentrifugation of Human Serum Albumin complexed with Porphyrin <p style="margin-right: 0px; margin-bottom: 0px; margin-left: 0px;">Analytical Ultracentrifugation (AUC) is the method of choice to characterize colloidal systems under physiological solution conditions.</p> <p style="margin-right: 0px; margin-bottom: 0px; margin-left: 0px;">Recently, a novel multi-wavelength (MWL) detector on Beckman Coulter&rsquo;s Optima AUC has been developed, which for the first time, couples the hydrodynamic separation of colloidal mixtures to spectral deconvolution of interacting and non-interacting solutes present in a mixture.</p>

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